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Does Trazodone Make You Fail A Drug Test?

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James Parnell Profile
James Parnell answered
Yes, Trazodone can make you fail a drug test. This is because it creates metabolite which is similar in its chemical construction to that of the illegal and abusive substance, MDMA.

Will Trazodone make you fail a drug test?
  • Trazodone (Molipaxin) is used to cure depression. It is sold in liquid, tablet and capsule form. It contains the active ingredient Trazodone hydrochloride.
  • Depression is a state in which you are anxious and abnormal physiologically. It is an incomprehensible and complex medical condition, which could be attributed to the actions and presence of substances in the brain.
  • There are two identified neurotransmitters in the brain: Noradrenaline and serotonin. When noradrenaline and serotonin are emitted by the nerve cells, it lightens one's temper or moods.
  • Depression occurs if the amounts of noradrenaline and serotonin released in the brain have reduced in number.
  • Trazodone performs its function by hindering the noradrenaline and serotonin being absorbed back to other nerve cells. Trazadone can also imitate the easing mood-effect of serotonin, and increase the release of noradrenaline.
  • Trazadone is primarily used to cure depression, sleep disturbances and anxiety.
If you are about to undertake a drug screening, then it would be advisable to take a doctor's note and prescription form to the test - to prove to the technician that it was the Trazodone that caused the false result and not the presence of MDMA in your system.
Anonymous Profile
Anonymous answered
Yes. I just took a drug test for the department of corrections. Trazadone showed up as a methamphetamine.

I'm on 7 prescription drugs, and, at the first test, I hadn't taken Trazadone the night before and came up negative.

The only change I made was take Trazadone the night before the second and third tests - and they came up positive.

But then again I'm only a sample size of 1 vs the 40 randomized persons you would need for a randomized study.

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