Yes.Norco is an opiate schedule 3. It will be positive on a drug screen. Under opiates.If you have a legit rx from a doctor . You can take the paperwork in and prove your reasons for this medication. I dont know what your drug test is for, but having the rx of a pain med would not hurt you. This could prove that you honestly need the medicine and have legit paperwork you could or should be ok in most situations best of luck