Hydrocodone stays in the blood stream 6-24 hours.
Hydro can be detected up to 30 days for a blood test. Anyone worried about detection should seek treatment for addiction. This medication is to be used for real pain problems only and it needs to be RXed by an MD that has evaluated the person. Doctors are becoming afraid to RX pain meds to those of us with MS because so many others have no real pain while seeking pain meds!