Depends on the drugs you r getting rid of. Narcotics r usually in there for 3-5 days, same for benzos. Pot the most harmless (IMHO) lasts the longest. That said if you got loot go to a head shop or a store that sells drug paraphernalia (scales,bongs,packaging materials,etc.) usually found in a ghetto area (at least where I live anyways) & buy that stuff in a plastic bottle, its usually thick & requires you to chug it down w/water & tastes funky. It's a regimented set of instructions but if followed to a "T" your pee will be as clean as a new born babies born to an Amish couple!