It would but the dr reading the test would know it wasnt illegal
Does Benadryl Show Up As Amphetamine On A Drug Test?
I have taken four benadryl every night for the past two years and I have had surgery five times in the past two years I tell all the dr's and the anesthesiologist's about the benadryl and they don't blink and eye, so I'm guessing it's not a big deal like they think lortab is.