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Will flexeril show up on a hair follicle drug test?

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Iris Phillips answered
Flexeril, or Cyclobenzaprine, is a muscle relaxant which works by blocking nerve impulses or sensations of pain sent to the brain. In theory, it should not show on the test, although it appears that occasionally it may do so, especially if used in combination with other drugs.

As it is a prescription drug, this should not be a problem, as long as proof can be provided that it was prescribed by a doctor for the individual. Considering the potentially fatal side-effects of this drug, especially in combination with other drugs including alcohol, one can only hope that no-one would consider taking it for anything other than a solid medical reason.

After a substance has been introduced into the body, whether it has been taken orally, smoked, snorted or injected, the human body produces metabolites while processing the drug. As both the drug and produced metabolites circulate through the bloodstream, some of them will enter and consequently nourish the hair follicle and end up in the strand of hair.

For a standard test, the sample of hair is cut as close to the individual's scalp as possible. About 3.9 cm (1.5 in) of the most recent growth is then tested. This will cover a period of around 90 days, although there may be a slight variation to this time period depending on varying growth rates of hair between individuals. It is possible to go further back in time by using a longer sample of hair, but the 90 day period is used as a standard.

Standard hair follicle tests are usually employed to detect five different classes of drugs:
  • Cocaine, which includes Cocaine and Benzoylecgonine
  • Marijuana
  • Opiates, including Codeine, Morphine and 6 - Monacteyl Morphine
  • Methamphetamine, Amphetamine and Ecstasy
  • Phencyclidine, usually referred to as PCP

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