Will Phenergan Show Up As A Barbiturate On A Drug Test?

Yes, Phenergan could possibly show up as a barbiturate on a standard drug screening, and therefore could produce a false-positive result.

Barbiturates are one of the ten substances tested for in a ten panel drugs screening.

The quality of the lab and the sample will determine how accurate each drug test is, so if you're taking Phenergan, then notify the technician before the test. 

Is Phenergan a Barbiturate?

• Phenergan (promethazine) treats travel sickness, jet lag, and allergies. It is sold in elixir and tablet form, and contains promethazine hydrochloride - which belongs to the family of medicines known as sedating antihistamines.
• It functions as a beta blocker, preventing histamine from being produced and multiplying inside the human body.
• Histamine is among the substances produced in the body as part of its defence mechanism, but it also causes symptoms of different allergic reactions. These include the inflammation of airways, narrowing of the airways, nasal congestion, and itching and rashes of the skin, eyes and nose.
• Promethazine prevents histamine from binding to the receptors in various parts of the body, causing the symptoms of allergic reaction.
• Promethazine also blocks histamine receptors in the area of the brain known as the vomiting centre, which is responsible for inducing feelings of being sick and vomiting reflexes. It is triggered by nerve messages on the vestibular apparatus of the ear.